Thyroid Antibodies

In addition to screening for the thyroid hormones that play a key role in regulating metabolism, this advanced thyroid function test detects and measures the quantity of specific thyroid autoantibodies to determine whether autoimmune disease may be impacting thyroid function.

• TPOAb

  Thyroid peroxidase antibodies work against thyroid peroxidase, an enzyme that plays a part in the T4-to-T3 conversion and synthesis process. TPO antibodies can be evidence of tissue destruction, such as Hashimoto’s disease.

• TGAb

  When your immune system attacks the thyroid it often targets thyroglobulin which causes it to produce antithyroglobulin antibodies. Thyroglobulin antibodies are positive in about 60% of Hashimoto’s patients and 30% of Graves patients.